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Manufactured under stringent AHRI 700 and ASHRAE 34 quality standards, every product delivers reliable thermodynamic performance for air conditioning, commercial refrigeration, industrial cooling, fire suppression, and specialty applications worldwide. [Explore Our Refrigerant Products](#products) **Do Sender Chem** supplies **premium HFC refrigerant products** manufactured under stringent quality controls and in full compliance with ** AHRI 700 ** and ** ASHRAE 34 ** standards. Our refrigerant portfolio features industry-leading purity levels, minimal moisture and non-condensable gas content, and consistent thermodynamic performance. With flexible packaging options from returnable cylinders to ISO tank containers, we serve HVAC manufacturers, refrigeration service providers, and automotive air conditioning systems worldwide. Why Choose Us ## Why Choose Our ** Refrigerants ** Precision-manufactured refrigerants delivering optimal cooling performance, regulatory compliance, and supply reliability. ✯ ### AHRI 700 Certified All refrigerant products meet or exceed AHRI Standard 700 purity specifications, ensuring reliable performance in every application. 🌎 ### Environmental Compliance Products comply with the Montreal Protocol, Kigali Amendment, and regional F-gas regulations for responsible environmental stewardship. ⚙ ### Consistent Purity ≥ 99.9% Rigorous multi-stage purification and batch testing guarantee consistent purity levels, maximizing system efficiency and equipment lifetime. 📦 ### Flexible Supply Chain Returnable cylinders, disposable cylinders, drums, and ISO tank containers with global logistics for on-time delivery anywhere. Applications ## Key **Applications** Our HFC refrigerants power a broad spectrum of cooling and refrigeration systems across industries. ❄Residential Air Conditioning ❄Commercial HVAC ❄Industrial Process Cooling 🏭Cold Storage Warehousing 🏭Cold Chain Logistics 🏭Food & Beverage Refrigeration 🚗Automotive Air Conditioning 🚗Transport Refrigeration 🏨Data Center Cooling 🏨Medical Refrigeration Products ## Complete **Refrigerant Portfolio** 21 refrigerant products manufactured to AHRI 700 and ASHRAE 34 standards. Each product card details uses, packaging options, and transport classification. ### Standard HFC / HCFC / HFO Refrigerants HCFC • Phasedown ### R22 CAS: 75-45-6 | Formula: CHClF₂ Uses Legacy refrigerant for residential and commercial air conditioning, industrial process cooling, and medium-temperature refrigeration. Being phased out under the Montreal Protocol; limited availability for servicing existing equipment in approved regions. Packaging Returnable steel cylinders (13.6 kg, 22.7 kg, 45.4 kg); disposable cylinders (13.6 kg). UN 1018 Class 2.2 Boiling Pt. -40.8°C [Inquire about R22 →](#contact) HFC Refrigerant ### R23 CAS: 75-46-7 | Formula: CHF₃ Uses Ultra-low-temperature refrigerant for cascade refrigeration systems, environmental test chambers, and medical cryogenic storage. Also used in fire suppression systems (FE-13) and as a low-temperature heat transfer fluid. Packaging Returnable high-pressure steel cylinders (5 kg, 9 kg, 40 kg); ISO tank containers for bulk supply. UN 3136 Class 2.2 GWP 14,800 [Inquire about R23 →](#contact) HFC Refrigerant ### R32 CAS: 75-10-5 | Formula: CH₂F₂ Uses Single-component HFC for next-generation residential and commercial air conditioning and heat pump systems. Preferred low-GWP alternative to R-410A; requires smaller refrigerant charge per system. Widely adopted in split-system AC units globally. Packaging Returnable steel cylinders (10 kg, 22.7 kg); disposable cylinders (10 kg); ISO tanks available. UN 3252 Class 2.1 (A2L) GWP 675 [Inquire about R32 →](#contact) HFC Refrigerant ### R143A CAS: 420-46-2 | Formula: CF₃CH₃ Uses Key blend component in R-404A, R-507A, and R-428A formulations. Used primarily in low-temperature commercial refrigeration blends. Also applied as a specialty aerosol propellant where non-flammability is critical. Packaging Returnable steel cylinders (10 kg, 22.7 kg); ISO tank containers for blend manufacturers. UN 3163 Class 2.1 GWP 4,470 [Inquire about R143A →](#contact) HFC Refrigerant ### R134A CAS: 811-97-2 | Formula: CH₂FCF₃ Uses Industry-standard HFC for automotive air conditioning, medium-temperature commercial refrigeration, domestic refrigerators, centrifugal chillers, and pharmaceutical processing. Non-flammable (A1), thermally stable, and widely compatible. Packaging Returnable steel cylinders (13.6 kg, 22.7 kg); disposable cylinders; 100-1000 kg drums; ISO tank containers. UN 3159 Class 2.2 GWP 1,430 [Inquire about R134A →](#contact) HFC Refrigerant ### R125 CAS: 354-33-6 | Formula: CHF₂CF₃ Uses Core blend component for R-410A, R-404A, R-407C, and R-507A. Also deployed as a clean fire suppression agent (FE-25) in occupied spaces, data centers, museums, and telecommunications facilities where water-based suppression is unsuitable. Packaging Returnable high-pressure steel cylinders (11.3 kg, 22.7 kg); ISO tanks for bulk blending operations. UN 3220 Class 2.2 GWP 3,500 [Inquire about R125 →](#contact) HFC Refrigerant ### R152A CAS: 75-37-6 | Formula: CH₃CHF₂ Uses Low-GWP refrigerant for medium-temperature applications, automotive AC (secondary loop systems), and domestic refrigeration. Also used as an aerosol propellant and foam-blowing agent. Excellent energy efficiency with a GWP of only 124. Packaging Returnable steel cylinders (10 kg, 22.7 kg); disposable cans for aerosol-grade material. UN 1030 Class 2.1 (A2) GWP 124 [Inquire about R152A →](#contact) Blend Refrigerant ### R404A CAS: 354-33-6 / 420-46-2 / 811-97-2 | R-125/R-143a/R-134a Uses Near-azeotropic HFC blend for low- and medium-temperature commercial refrigeration: supermarket freezers, walk-in coolers, refrigerated transport, ice machines, and cold storage warehouses. Excellent capacity at low evaporator temperatures. Packaging Returnable cylinders (10 kg, 22.7 kg, 45.4 kg); disposable cylinders; ISO tank containers; drums (100-1000 kg). UN 3337 Class 2.2 (A1) GWP 3,922 [Inquire about R404A →](#contact) Blend Refrigerant ### R407C CAS: 354-33-6 / 811-97-2 / 75-10-5 | R-125/R-134a/R-32 Uses Zeotropic HFC blend designed as an R-22 retrofit for medium-temperature AC and heat pump systems in commercial buildings, process chillers, and residential HVAC. Delivers performance close to R-22 with minimal equipment modifications. Packaging Returnable cylinders (11.3 kg, 22.7 kg); disposable cylinders; ISO tanks for large retrofits. UN 3340 Class 2.2 (A1) GWP 1,774 [Inquire about R407C →](#contact) Blend Refrigerant ### R410A CAS: 354-33-6 / 75-10-5 | R-125/R-32 (50/50 wt%) Uses High-pressure near-azeotropic blend for residential and light commercial air conditioning and heat pump systems. Higher cooling capacity than R-22; operates at ~60% higher pressure. The leading refrigerant for new unitary AC equipment worldwide. Packaging Returnable cylinders (11.3 kg, 22.7 kg); disposable cylinders; ISO tank containers; drums. UN 3163 Class 2.2 (A1) GWP 2,088 [Inquire about R410A →](#contact) Blend Refrigerant ### R507A CAS: 354-33-6 / 420-46-2 | R-125/R-143a (50/50 wt%) Uses Azeotropic HFC blend for low-temperature commercial and industrial refrigeration: cold storage, food processing, ice rinks, and transport refrigeration. Behaves as a single substance with no temperature glide, simplifying system design. Packaging Returnable steel cylinders (10 kg, 22.7 kg); disposable cylinders; ISO tank containers. UN 3337 Class 2.2 (A1) GWP 3,985 [Inquire about R507A →](#contact) HFO Refrigerant ### R1234yf CAS: 754-12-1 | Formula: CF₃CF=CH₂ Uses Next-generation HFO refrigerant for automotive air conditioning (OEM), meeting EU MAC Directive and Kigali Amendment requirements. Ultra-low GWP of 4, with performance closely matching R-134a. Increasingly adopted in new vehicle platforms worldwide. Packaging Returnable steel cylinders (5 kg, 10 kg); ISO tank containers for automotive OEM supply. UN 3161 Class 2.1 (A2L) GWP 4 [Inquire about R1234yf →](#contact) ### Specialty & CFC Refrigerants CFC • Phased Out ### R12 CAS: 75-71-8 | Formula: CCl₂F₂ Uses Legacy CFC refrigerant formerly used in automotive AC, domestic refrigerators, and centrifugal chillers. Production phased out globally under the Montreal Protocol since 2010. Limited availability for essential uses (MDIs, laboratory applications) only. Packaging Returnable steel cylinders (13.6 kg); supply strictly controlled for approved essential-use applications. UN 1028 Class 2.2 ODP 1.0 [Inquire about R12 →](#contact) Specialty Refrigerant ### R116 CAS: 76-16-4 | Formula: C₂F₆ Uses Ultra-low-temperature refrigerant (boiling point -78.2°C) for cascade refrigeration systems, semiconductor plasma etching and chamber cleaning, and specialty low-temperature research applications. Delivers stable performance at extreme cold. Packaging Returnable high-pressure steel cylinders (5 kg, 20 kg); specialized cryogenic transport containers. UN 2193 Class 2.2 GWP 12,200 [Inquire about R116 →](#contact) Specialty Refrigerant ### RC318 CAS: 115-25-3 | Formula: c-C₄F₈ Uses Specialty PFC used in semiconductor manufacturing as a plasma etching and chamber cleaning gas for advanced node processes. Also applied in specialized low-temperature refrigeration cycles requiring high chemical stability. Packaging High-purity returnable cylinders (5 kg, 10 kg); electronic-grade quality for semiconductor fabs. UN 3156 Class 2.2 GWP 10,300 [Inquire about RC318 →](#contact) Specialty Refrigerant ### R13B1 CAS: 75-63-8 | Formula: CBrF₃ Uses Halon 1301 fire suppression agent for aviation (engine nacelles, cargo bays), military vehicles, and specialized industrial protection. Also used historically as a low-temperature refrigerant. Supply regulated under the Montreal Protocol. Packaging Returnable high-pressure cylinders (10 kg, 25 kg); restricted supply for approved critical-use fire suppression only. UN 1009 Class 2.2 ODP 10 [Inquire about R13B1 →](#contact) Specialty • Limited ### R40 CAS: 74-87-3 | Formula: CH₃Cl Uses Historically used as an early refrigerant. Currently applied as a methylating agent in chemical synthesis, a specialty solvent, and a chemical intermediate for silicone polymers, pharmaceuticals, and agrochemicals production. Packaging Returnable steel cylinders (40 kg, 100 kg); ISO tank containers for chemical manufacturing supply. UN 1063 Class 2.1 Toxic / Flammable [Inquire about R40 →](#contact) HCFC Refrigerant ### R1113 CAS: 79-38-9 | Formula: CClF=CF₂ Uses Specialty chlorofluoroolefin used as a chemical intermediate in fluoropolymer and specialty chemical synthesis. Limited refrigeration applications in specialized low-temperature cascade systems requiring high chemical stability. Packaging Returnable high-pressure cylinders (5 kg, 10 kg); temperature-controlled transport for product stability. UN 1082 Class 2.1 Stabilizer Required [Inquire about R1113 →](#contact) HCFC Refrigerant ### R124 CAS: 63938-10-3 | Formula: CHClFCF₃ Uses Medium-temperature HCFC refrigerant for centrifugal chillers, heat pump systems, and industrial process cooling. Also serves as a fire suppression agent (FE-241) for total-flooding applications in occupied and unoccupied spaces. Packaging Returnable steel cylinders (11.3 kg, 22.7 kg); ISO tank containers for chiller service and retrofits. UN 1021 Class 2.2 GWP 609 [Inquire about R124 →](#contact) Specifications ## Technical **Reference Data** Key physical properties, safety classifications, and regulatory identifiers for our complete refrigerant portfolio. Request detailed specification sheets for individual products. Product Type CAS No. Boiling Pt. GWP Safety UN No. R22HCFC75-45-6-40.8°C1,810A1UN 1018 R23HFC75-46-7-82.1°C14,800A1UN 3136 R32HFC75-10-5-51.7°C675A2LUN 3252 R143AHFC420-46-2-47.2°C4,470A2UN 3163 R134AHFC811-97-2-26.3°C1,430A1UN 3159 R125HFC354-33-6-48.1°C3,500A1UN 3220 R152AHFC75-37-6-24.0°C124A2UN 1030 R404ABlend See card -46.5°C3,922A1UN 3337 R407CBlend See card -43.8°C1,774A1UN 3340 R410ABlend See card -51.6°C2,088A1UN 3163 R507ABlend See card -47.1°C3,985A1UN 3337 R1234yfHFO754-12-1-29.4°C4A2LUN 3161 R12CFC75-71-8-29.8°C10,900A1UN 1028 R116PFC76-16-4-78.2°C12,200A1UN 2193 RC318PFC115-25-3-6.0°C10,300A1UN 3156 R13B1Halon75-63-8-57.8°C7,140A1UN 1009 R40Specialty74-87-3-24.2°C13A2UN 1063 R1113HCFC79-38-9-28.0°CN/AA2UN 1082 R124HCFC63938-10-3-12.0°C609A1UN 1021 Safety classifications per ASHRAE Standard 34. GWP values per IPCC AR5 (100-year). Detailed specification sheets, SDS, and Certificates of Analysis available upon request. Quality & Safety ## Quality Assurance & **Safe Handling** Our refrigerant products are manufactured, tested, packaged, and shipped under rigorous quality management and safety protocols. ⚠ Refrigerant products are pressurized gases/liquefied gases and must be handled, stored, and transported in accordance with applicable regulations. Store cylinders in cool, dry, well-ventilated areas away from heat sources and direct sunlight. Use appropriate personal protective equipment (PPE) including safety goggles and gloves when handling. **Always consult the Safety Data Sheet (SDS) before use. 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